Resources

Key Publications

ResistancePlus™

Tabrizi S., Tan Y.L., Walker S., Twin J., Poljak M., Bradshaw C.S., Fairley C.K., Bissessor M., Mokany E., Todd A.V., Garland S.M., 2016. Multiplex assay for simultaneous detection of Mycoplasma genitalium and macrolide resistance using PlexZyme and PlexPrime technology. PLOS ONE June 6th.
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PlexZyme™

Mokany E., Tan Y.L., Bone S.M., Fuery C., Todd A.V., 2013. MNAzyme qPCR with superior multiplexing capacity. Clin. Chem. 59(2); 419-426
Link | Supplementary Information

Mokany E., Bone S.M., Young P.E., Doan T.M., Todd A.V., 2010. MNAzymes are a versatile new class of nucleic acid enzymes which can function as biosensors and molecular switches. J. Am. Chem. Soc. 132(3); 1051-1059
Link |Supplementary Information

Tan L. Y., Walker S. M., Lonergan T., Lima N. E., Todd A. V. Mokany E. 2017. Superior Multiplexing Capacity of PlexPrimers Enables Sensitive and Specific Detection of SNPs and Cluster Mutations in qPCR. PLOS One January 23rd.
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Signal Amplification

Linardy E.M., Erskine S.M., Lima N.E., Lonergan T., Mokany E., Todd A.V., 2016. EzyAmp signal amplification cascade enables isothermal detection of nucleic acid and protein targets. Biosens. Bioelectron. 75; 59-66
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Bone S.M., Lima N.E., Todd A.V., 2015. DNAzyme switches for molecular computation and signal amplification. Biosens. Bioelectron. 70; 330-337
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Bone S.M., Todd A.V., 2014. MNAzymes provide a universal mechanism for triggering DNAzyme synthesis cascades. Chem. Comm. 50(87); 13243-13246
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Bone S.M., Hasick N.J., Lima N.E., Erskine S.M., Mokany E., Todd A.V., 2014. DNA-only Cascade: a universal tool for signal amplification, enhancing the detection of target analytes. Anal. Chem. 86(18); 9106-9113
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Related Publications

Nature Review
Jensen J.S. & Unemo M. 2017 Antimicrobial-resistant sexually transmitted infections: gonorrhoea and Mycoplasma genitalium. Nature Review Urology January 10th.
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Mycoplasma genitalium IUSTI guidelines
Jensen J.S., Cusini M., Gomberg M. 2016. 2016 European guideline on Mycoplasma genitalium infections. IUSTI June 2nd.
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Zagorovsky K. and Chan W.C.W. 2013. A plasmonic DNAzyme strategy for point-of-care genetic detection of infectious pathogens. Angew. Chem. 52(11); 3168-3171
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Kahan-Hanum M., Douek Y., Adar R., Shapiro E. 2013. A library of programmable DNAzymes that operate in a cellular environment. Sci Rep. 3; 1535 Gerasimova Y.V. and Kolpashchikov D.M. 2010. Nucleic acid detection using MNAzymes. Chem. Biol. 17(2); 104-106
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Nauwelaers D., Vjigen L., Atkinson C., Todd A., Geretti A.M., Van Ranst M., Stuyver L. 2009. Development of a real-time multiplex RSV detection assay for difficult respiratory samples, using ultrasone waves and MNAzyme technology
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